Showing 1871-1880 of 2105 results for "".
- Cenobamate Reduces Antiseizure Medication Use in Adults With Focal Onset Seizureshttps://practicalneurology.com/news/cenobamate-reduces-antiseizure-medication-use-in-adults-with-focal-onset-seizures/2470080/Adults with focal onset seizures (also known as partial seizures) treated with cenobamate (Xcopri, SK Life Science, Paramus, NJ) experienced a 29% reduction in concomitant antiseizure medication use after 1 year and a 32% reduction after 2 years, according to research presented at the American Ep
- FDA Issues Refusal To File Letter for New Biologics License Application for Stem Cell ALS Treatmenthttps://practicalneurology.com/news/fda-does-not-file-new-biologics-license-application-for-stem-cell-amyotrophic-lateral-sclerosis-treatment/2470068/The Food and Drug Administration (FDA) has issued a refusal to file letter for the Biologics License Application (BLA) for autologous neurotrophic factor-secreting mesenchymal stem cells (MSC-NTF)(NurOwn; BrainStorm Cell Therapeutics, New York, NY) as treatment of amyotrophic lateral sclerosis (A
- First Participant in Phase 2/3 study of Trehalose Injection in Spinocerebellar Ataxiahttps://practicalneurology.com/news/first-participant-in-phase-23-study-of-trehalose-injection-in-spinocerebellar-ataxia/2470055/In the STRIDES study (NCT05490563), the first participant received a dose of 90.5 mg/mL trehalose injection (SLS-005; Seelos Therapeutics, New York, NY) for the treatment of type 3 spinocerebellar
- Neurotrophic Factor-Secreting Stem Cell Treatment Improves Function in Progressive Multiple Sclerosishttps://practicalneurology.com/news/neurotrophic-factor-secreting-stem-cell-treatment-improves-function-in-progressive-multiple-sclerosis/2470024/As published in Multiple Sclerosis, off-the-shelf growth factor-secreting stem cell (MSC-NTF) (NurOwn; BrainStorm Cell Therapeutics, New York, NY) treatment of people with progressive multiple sclerosis (MS) im
- Ecopipam Reduced Tics in Children and Adolescents With Tourette Syndromehttps://practicalneurology.com/news/ecopipam-reduced-tics-in-children-and-adolescents-with-tourette-syndrome/2470022/A recent study demonstrated efficacy and safety of ecopipam for treatment of Tourette syndrome (TS) in children and adolescents, ages 6 to 17 years. Both motor and phonic tics were reduced with ecopipam (n=74) compared with placebo (n=75). A statistically significant least
- Phase 3 Trial of Dextromethorphan-Bupropion for Agitation in Alzheimer Diseasehttps://practicalneurology.com/news/phase-3-trial-of-dextromethorphan-bupropion-for-agitation-in-alzheimer-disease/2470017/The first participant has been enrolled in the Addressing Dementia via Agitation-Centered Evaluation-2 (ADVANCE-2) trial (NCT03226522) of dextromethorphan-bupropion (AXS-05; Axsome Therapeutics, New York, NY), an investigational treatm
- New Intracranial Catheter System Provided Effective Clot Removal to Treat Middle Cerebral Artery Occlusions Causing Ischemic Strokehttps://practicalneurology.com/news/new-intracranial-catheter-system-provided-effective-clot-removal-to-treat-middle-cerebral-artery-occlusions-causing-ischemic-stroke/2470009/An intracranial catheter systtem (Zoom Stroke Solution; Imperative Care, Campbell, CA) for middle cerebral artery (MCA) M2 occlusions provided fast clot removal and reperfusion. In a single-center study, the majority of participants (92.7%) achieved Thrombolysis in Cerebral Infarction (TICI) 2b/3
- Rates and Outcomes of Concussion Affected by Intensity Hits and Family History of Dementiahttps://practicalneurology.com/news/rates-and-outcomes-of-concussion-affected-by-intensity-hits-and-family-history-of-dementia/2469993/Susceptibility to concussion may have a genetic component, and intensity of head impacts may better predict future consequences (eg, chronic traumatic encephalopathy [CTE]) better than years of play or number of hits to the head. In a study of active boxers and mixed martial arts
- Visual Impairment in Hispanic/Latinx People May Be Associated With Worse Measures of Cognitionhttps://practicalneurology.com/news/visual-impairment-in-hispaniclatinx-people-may-be-associated-with-worse-measures-of-cognition/2469980/In a study conducted at the University of Miami Miller School of Medicine, Hispanic/Latinx people with self-reported vision problems had worse verbal fluency, memory, and processing speed/executive function). This correlation was found both at baseline and after 7 years of follow-up, with visual
- Immuno-Infrared Sensor is Able to Identify Symptom-Free Alzheimer Diseasehttps://practicalneurology.com/news/immuno-infrared-sensor-is-able-to-identify-symptom-free-alzheimer-disease/2469972/Alzheimer disease (AD) is thought to begin 15 to 20 years before clinical symptoms are seen, making early identification of presymptomatic disease a priority. As published in the journal Alzheimer’s & Dementia, new results compared sensitivity of an immune-infrared sensor with the compl