Headache in the Spotlight

New treatments are bringing the field of headache medicine to center stage.

Deena Kuruvilla, MD

About the Cover Artist

Migraine Mimics

Are we underdiagnosing migraines?

Cynthia E. Armand, MD; Alina Masters-Israilov, MD; and Richard B. Lipton, MD

Migraine Preventive Therapies

With new—and first-in-class—migraine-specific treatments, preventive treatment of migraine is changing quickly.

Charisse Litchman, MD, FAHS; and Sirisha Sanamandra, MBBS

Migraine Preventive Therapies in Development

The field of headache medicine is full of promise with more migraine-specific preventive therapies in development.

Aniket Natekar, MD, MSc; Malya Sahu, BSc; Hsiangkuo Yuan, MD, PhD; and Stephanie Nahas, MD, MSEd, FAHS, FAAAN

Migraine Acute Therapies

Acute treatment of migraine improves daily function and reduces associated disability and risk of transformation to chronic migraine.

Rashmi B. Halker Singh, MD; Amaal J. Starling, MD; and Juliana VanderPluym, MD

Migraine in Children

Headache is common in children and adolescents and there are exciting developments in diagnosis, classification, and treatment.

Lauren Doyle Strauss, DO, FAHS; and Scott Otallah, MD

Migraine During Pregnancy

Developing plans for treatment during pregnancy before conception can relieve stress for both patient and provider.

Kate Onorato, MD; Carrie Dougherty, MD, FAHS; and Jessica Ailani, MD, FAHS

Procedural Treatments for Headache Disorders

Botulinum toxin injections, nerve blocks, and trigger point injections are safe and effective in-office treatment options.

Regina Krel, MD; and Paul G. Mathew, MD, DNBPAS, FAAN, FAHS

Neuromodulation Therapies for Headache

Neuromodulation devices creates potential paradigm shift in headache medicine.

Umer Najib, MD, FAHS; Jessica Frey, MD; and David B. Watson, MD, FAHS, FAAN

Behavioral and Integrative Therapies for Headache

Many patients who may benefit from these treatments may not be aware nonpharmacologic approaches exist.

Mary Motwani, PhD; and Deena Kuruvilla, MD

Cannabis and Cannabinoid Therapies for Headache

Shown effective for treatment of pain, Cannabis may have benefits for patients with headache, but more research is still needed.

Niushen Zhang, MD

Cluster Headache Preventive Therapies

The challenges of cluster headache lead to treatments and further understanding.

Emmanuelle A. D. Schindler, MD, PhD; and Christopher Gottschalk, MD

Cluster Headache Acute Therapies

Despite strong evidence for high-flow oxygen, subcutaneous sumatriptan, and zolmitriptan nasal spray, patients often receive less-than-adequate abortive treatment.

Brian E. McGeeney, MD, MPH, MBA

Neuromuscular Notes: Genetics of Amyotrophic Lateral Sclerosis

Genetic discovery and the promise of gene therapy create hope for effective treatments and eventual prevention.

Katharine Nicholson, MD

Epilepsy Essentials: Chronobiology of Epilepsy

As we expand our understanding of seizure cycles, the new field of chronoepileptology begins.

Michelle L. Dougherty, MD, FAAN

Stroke Spotlight: Subarachnoid Hemorrhage and Cerebral Vasospasm

Cerebral vasospasm increases morbidity and mortality in persons with subarachnoid hemorrhage.

Saif A. Bushnaq, MD; and Sunil A. Sheth, MD

Dementia Insights: Cognitive Consequences of Perimenopause

A possible contribution of perimenopause should be considered when evaluating women with cognitive complaints.

Ronald Devere, MD, FAAN

Hometown Highlights: Procedural Treatments for Movement Disorders

The Philadelphia Neurologic Society explores the journey from thalamotomy to MR-guided focused ultrasound for movement disorders.

Gordon H. Baltuch, MD, PhD

Case Report: Hemiparkinsonism in a Patient With Multiple Sclerosis

In this case, there was a causal relationship between comorbid diseases.

Andrea P. Lee, MD; Giulietta M. Riboldi, MD; Ilya Kister, MD; Jonathan E. Howard, MD; and Ritesh A. Ramdhani, MD

Last Word: Eptinezumab on the Horizon

Alder BioPharmaceuticals has submitted an application for approval of an antibody to CGRP, unique for its 30-minute quarterly infusion and more.

Bob Azelby, MBA