New Intracranial Catheter System Provided Effective Clot Removal to Treat Middle Cerebral Artery Occlusions Causing Ischemic Stroke
An intracranial catheter systtem (Zoom Stroke Solution; Imperative Care, Campbell, CA) for middle cerebral artery (MCA) M2 occlusions provided fast clot removal and reperfusion. In a single-center study, the majority of participants (92.7%) achieved Thrombolysis in Cerebral Infarction (TICI) 2b/3 reperfusion scores. A TICI 2c/3 reperfusion score was achieved in over half (63.4% n=26/41) of participants.
The median score on the National Institute of Health Stroke decreased significantly from 10.5 (Interquartile Range [IQR] 7.0-14.5) at arrival to 1.5 (IQR 0-6.0) at discharge (P<.001). The average time from access to first aspiration attempt was 10 (IQR 6.6- 16.5) minutes and median time from access to final reperfusion was 21.5 (IQR 16.0-31.8) minutes.
“More and more physicians are treating distal vessel occlusions despite their location in the brain—which can be more challenging to reach than other types of occlusions—resulting in a meaningful clinical impact. We are pleased to see the results from this single-center experience demonstrating the unique capabilities of the Zoom Reperfusion Catheters for the treatment of MCA M2 segment occlusions,” said Daniel Davis, president and chief operating officer of Imperative Care.
“The Zoom Stroke Solution is the only system that pairs an intracranial access catheter, Zoom 88, with a range of purposefully designed vessel-matching reperfusion catheters, Zoom 35, 45, 55 and 71, and pump that can help reach these types of occlusions and enable fast and effective clot ingestion. We look forward to continued studies to evaluate mechanical thrombectomy in these vessels and further emphasize the clinical efficacy of our technology,” said Davis.
There was a single instance (2.4%) of symptomatic intracranial hemorrhage in this study cohort. However, no perforations or other reperfusion catheter related complications occurred.
"Distal vessel occlusions are considered the next frontier in mechanical thrombectomy for stroke treatment. The data from this study offer additional clinical evidence that aspiration thrombectomy using the Zoom Stroke Solution is both safe and effective for occlusions in the MCA M2 segment. Furthermore, Zoom 88 provides an excellent intracranial access catheter platform for distal occlusions. Even in the most tortuous cases, we have more than halved our procedural times with rapid initial and repeat passes to the distal circulation as needed,” said Dr. Colin Torok, neurointerventional surgeon and lead author of the study presented at Midwest Radiology in Minneapolis, MN.