the first time that a LRRK2 substrate has been fully validated by multiple labs, various tools and models, and molecular techniques. We are very confident that these Rab substrates—which play a role in cellular trafficking—will stand the test of time as bona fide proteins directly regulated by LRRK2. And this finding would not have happened without the open collaboration between academic laboratories and two major pharmaceutical companies, organized and facilitated by The Michael J. Fox Foundation.”