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Are Anti-amyloid Therapies Still Worth Being Developed as Treatments for Alzheimer's Disease?
https://practicalneurology.com/diseases-diagnoses/alzheimer-disease-dementias/are-anti-amyloid-therapies-still-worth-being-developed-as-treatments-for-alzheimers-disease/30832/Despite limited pharmaceutical success thus far, amyloid peptides may yet prove useful in the treatment of Alzheimer's and delay disease progression.About the Cover Artist: Rock Island by Rodrigo Duran
https://practicalneurology.com/diseases-diagnoses/neuromuscular/about-the-cover-artist-irock-islandi-by-rodrigo-duran/32122/Despite challenges associated with congenital muscular dystrophy and epilepsy, Rodrigo is still pursuing his goal of working in the art industry.- Keeping Stroke Patients Safe and Securehttps://practicalneurology.com/diseases-diagnoses/stroke/pn0807-stroke-fea-pdf/31139/Surviving an ischemic stroke brings immediate relief for patients, yet it introduces lifelong vulnerabilities, notably the risk of recurrent and potentially more severe strokes. Effective supportive care for stroke survivors centers on two primary objectives: minimizing injury to ischemic brain tiss
- Dementia Insightshttps://practicalneurology.com/diseases-diagnoses/alzheimer-disease-dementias/pn0607-demetia-insight-pdf/31160/In the June 2007 issue of *Practical Neurology*, Dr. David S. Geldmacher explores the challenges neurologists face with the outdated ICD-9-CM (International Classification of Disease, 9th Revision-Clinical Modification) coding system, particularly in diagnosing and managing dementia. Drawing an anal
- Expert Opinionhttps://practicalneurology.com/diseases-diagnoses/alzheimer-disease-dementias/PN0507ExpertOp-pdf/31176/Atypical Antipsychotics in Alzheimer’s Disease: Balancing Efficacy and SafetyIn a case report by Dr. Richard M. Sobel, a 79-year-old patient with Alzheimer’s disease (AD) exhibits progressive cognitive decline accompanied by memory loss, confusion, delusions of theft, and occasional combativeness. D
- Epilepsy Essentialshttps://practicalneurology.com/diseases-diagnoses/epilepsy-seizures/pn0307-epilepsy-pdf/31201/Epilepsy and migraine are frequently comorbid neurological disorders, with individuals diagnosed with epilepsy experiencing a higher prevalence of migraine than the general population. Approximately 24% of epilepsy patients and 26% of their relatives report migraines, compared to a 15% prevalence in
- Tackling the Challenges of Advanced Parkinson's Diseasehttps://practicalneurology.com/diseases-diagnoses/movement-disorders/pn1206parkinsonsfea-pdf/31241/Advanced Parkinson’s Disease: Clinical Challenges and Management StrategiesParkinson’s disease (PD) in its advanced stages presents a complex clinical landscape, extending beyond the classic motor symptoms of bradykinesia, rigidity, and tremor. While levodopa has significantly mitigated these primar
- Epilepsy Essentialshttps://practicalneurology.com/diseases-diagnoses/epilepsy-seizures/PN0406epilepsy-pdf/31326/Differentiating Seizures from Syncope: A Comprehensive Diagnostic ApproachEpisodes of loss of consciousness (LOC) present significant diagnostic challenges in both emergency departments (ED) and neurology clinics, accounting for approximately three percent of ED visits and one percent of hospital ad
- Epilepsy Essentialshttps://practicalneurology.com/diseases-diagnoses/epilepsy-seizures/PN1005epilepsy-pdf/31388/Exploring the Complex Interplay Between Epilepsy and Mood DisordersEpilepsy and depression frequently coexist as comorbid conditions, significantly impacting patients' quality of life. Comorbidity, defined as the simultaneous occurrence of two or more diseases, does not necessarily indicate causalit
- Achieving Freedom From AEDs Without Compromising Controlhttps://practicalneurology.com/columns/practice-management/achieving-freedom-from-aeds-without-compromising-control/31393/Tapering Antiepileptic Drugs: Balancing Seizure Control and Quality of LifeIn the October 2005 issue of *Practical Neurology*, Dr. Christopher Skidmore explores whether epilepsy necessitates lifelong antiepileptic drug (AED) therapy. Highlighting the dual objectives of achieving seizure control whil