Showing 1951-1960 of 2123 results for "".
- New Genetic Tests Available for Hereditary Ataxiashttps://practicalneurology.com/news/new-genetic-tests-available-for-hereditary-ataxias/2469486/Several genetic tests, including repeat-expansion analysis for spinocerebellar ataxia (SCA), Friedreich ataxia, and other common forms of hereditary ataxia have been newly made available by GeneDx (Gaithersberg, MD). The repeat-expansion analysis may be done concurrently with single nucleotide va
- Clinical Trial of Neuromodulation for Alzheimer Disease and Mild Cognitive Impairment Expandedhttps://practicalneurology.com/news/clinical-trial-of-neuromodulation-for-alzheimer-disease-and-mild-cognitive-impairment-expanded/2469463/Clinical trials of transcranial direct current stimulation (tDCS)(ElectraRx; Soterix Medical, New York, NY) for potential treatment of Alzheimer disease (AD), mild cognitive impairment (MCI), and age-related cognitive decline have been expanded. The study of the proprietary neurostimulation devic
- Long-Term Freedom from Seizure With Perampanel Treatmenthttps://practicalneurology.com/news/long-term-freedom-from-seizure-with-perampanel-treatment/2469455/In a post-hoc analysis, of the phase 3 FREEDOM study (NCT03201900), 62.5% of individuals treated with 4 to 8 mg/day of perampanel (Fycompa, Eisai Inc, Woodcliff Lake, NJ) achieved seizure freedom for 1 year. Participants in the study w
- Anxiety and Depression Prevalence in Children and Adolescents With Epilepsyhttps://practicalneurology.com/news/anxiety-and-depression-prevalence-in-children-and-adolescents-with-epilepsy/2469453/According to research presented virtually at American Epilepsy Society AES2020, children and adolescents with epilepsy are more likely to have anxiety and depression, including suicidal thinking, then previously considered. In a study of 119 children age 9 to 18 years, none of who
- Laser Thermal Ablation Therapy Brings Seizure Freedom to 54% of Children Treatedhttps://practicalneurology.com/news/laser-thermal-ablation-therapy-brings-seizure-freedom-to-54-of-children-treated/2469450/A new study being presented virtually at American Epilepsy Society AES2020 showed MRI-guided laser interstitial thermal therapy (MR-LITT) in children with medically refractory epilepsy, achieved seizure freedom for 54% 1 year after the procedure. Children treated (n=182) were age 14 months of age
- Vatiquinone Phase 3 Trial Initiated for Potential Treatment of Friedreich Ataxiahttps://practicalneurology.com/news/vatiquinone-phase-3-trial-initiated-for-potential-treatment-of-friedreich-ataxia/2469445/The registration-directed phase 3 MOVE-FA study (NCT04577352) evaluating vatiquinone (PTC743; PTC Therapeutics, South Plainfield, NJ) in children and young adults with Friedreich ataxia (FA) has b
- Potential Pediatric Use of New Migraine Therapieshttps://practicalneurology.com/news/potential-pediatric-use-of-new-migraine-therapies/2469437/Over the past 10 years multiple new treatments have been approved for use in adults. However, there has been little improvement in treatments specifically indicated for treatment of migraine in children, and very little data on the effects of these medications in children are available. At the Vi
- Stem Cell Treatment Responses Fails to Reach Statistical Significance and Has High Placebo Response Ratehttps://practicalneurology.com/news/stem-cell-treatment-responses-fails-to-reach-statistical-significance-and-has-high-placebo-response-rate/2469434/In a phase 3 clinical trial (NCT03280056) of autologous neurotrophic factor-secreting mesenchymal stem cells (MSC-NTF)(NurOwn; BrainStorm Cell Therapeutics, New York, NY), 34.7% of participants wi
- FDA Approves Lacosamide for Primary Generalized Tonic-Clonic Seizures and Expanded Pediatric Usehttps://practicalneurology.com/news/fda-approves-lacosamide-for-primary-generalized-tonic-clonic-seizures-and-expanded-pediatric-use/2469432/The Food and Drug Administration (FDA) has approved lacosamide (Vimpat; UCB, Atlanta, GA) as adjunctive therapy for primary generalized tonic-clonic seizures (PGTCS) in children age 4 years or more and lacosamide injection for intravenous use. Results from a phase 3 study (
- Posttraumatic Stress Disorder Symptoms Increase Over Time After Concussionhttps://practicalneurology.com/news/over-time-the-effects-of-concussions-may-evolve-in-veterans/2469426/A study published in Neurology, suggest concussion (mild traumatic brain injury [mTBI]) symptoms can last as long as 5 years and evolve over time. The study evaluated and compared veterans (n=281) with an