Showing 1621-1630 of 1692 results for "".
- Liquid Suspension of Zonisamide Available for Oral Administration to Treat Partial Seizures in Adultshttps://practicalneurology.com/news/liquid-suspension-of-zonisamide-available-for-oral-administration-to-treat-partial-seizures-in-adults/2470047/Zonisamide (Zonisade; Azurity Pharmaceuticals, Woburn, MA), an antiseizure medication for treatment of partial seizures, will become available as a liquid suspension (100 mg/5 mL) in retail pharmacies on October 17, 2022. The oral liquid formulation of zonisamide is FDA- approved and is the only
- Transdermal Donepezil Now Available in UShttps://practicalneurology.com/news/transdermal-donepezil-now-available-in-us/2470041/A once-weekly delivery system for donepezil (Adlarity; Corium, Boston, MA) is now available for prescription in the US. Transdermal donepezil was approved for for treating patients with mild, moderate, or severe dementia due to Alzheimer disease in March 2022. This formulation of
- Virtual Reality Experience May Aid Parkinson Disease Diagnosis and Gait Evaluationhttps://practicalneurology.com/news/virtual-reality-experience-may-aid-parkinson-disease-diagnosis-and-gait-evaluation/2469992/Researchers at Cleveland Clinic have developed a virtual reality (VR) experience with the intention of using the platform to identify early-stage Parkinson disease (PD) and better treat freezing of gait in individuals with PD. The VR platform (Infinadeck; Infinadeck, Rocklin, CA)
- Transdermal Donepezil Provides Drug Delivery Equivalent to Oral Donezepil With Favorable GI Side Effect Profilehttps://practicalneurology.com/news/transdermal-donepezil-provides-drug-delivery-equivalent-to-oral-therapy-with-favorable-gi-side-effect-profile/2469989/Results from a phase 1 trial (NCT04617782) show that both strengths of a donepezil transdermal system (Adlarity; Corium, Boston, MA) maintain equivalent daily exposure of donepezil compared to oral formulations of the drug and have a f
- Diazepam Nasal Spray for Acute Treatment of Seizure Clusters Easy to Use and Maintained Quality of Lifehttps://practicalneurology.com/news/diazepam-nasal-spray-for-acute-treatment-of-seizure-clusters-easy-to-use-and-maintained-quality-of-life/2469878/**This article was updated on April 13, 2022 to correct an error regarding the relative bioavailability of diazepam nasal spray (Valtoco; Neurelis, San Diego, CA) compared with other formulations of diazepam. New data from the clinical development program for diazepam nasal spr
- Once-at-Bedtime Sodium Oxybate Therapy for Narcolepsy Preferred Among Patients and Clinicianshttps://practicalneurology.com/news/once-at-bedtime-sodium-oxybate-therapy-for-narcolepsy-preferred-among-patients-and-clinicians/2469855/Sodium oxybate therapy (FT218; Avadel Pharmaceuticals, Chesterfield, MO) with once-nightly dosing was preferred in a discrete choice experiment over twice-nightly dosing. Clinical trial results also show that this formulation of sodium oxybate improved daytime sleepiness, sleep quality, and refre
- Oral Solution of Celecoxib Becoming Available for Acute Migraine Treatmenthttps://practicalneurology.com/news/oral-solution-of-celecoxib-becoming-available-for-acute-migraine-treatment/2469757/Oral celecoxib (Elyxyb; BioDelivery Sciences International, Raleigh, NC and Dr. Reddy's Laboratories, Hyderabad, India) is a ready-to-use oral solution for the acute treatment of migraine, with or without aura, in adults. This formulation of celecoxib is currently not available in the US and
- First Patient Enrolled for Oral Edaravone Amyotrophic Lateral Sclerosis Treatmenthttps://practicalneurology.com/news/first-patient-enrolled-for-oral-edaravone-amyotrophic-lateral-sclerosis-treatment/2469741/The amyotrophic lateral sclerosis (ALS) Deceleration with ORal Edaravone (ADORE) phase 3 clinical trial for an oral formulation of edaravone (FNP122; Ferrer, Barcelona, Spain) has enrolled the first participant. The trial is being conducted in Europe and will enroll approximately 300 participants
- Extended-Release Carbidopa/Levodopa Improves Motor Fluctuations in Parkinson Diseasehttps://practicalneurology.com/news/extended-release-carbidopalevodopa-improves-motor-fluctuations-in-parkinson-disease/2469676/Data from a clinical trial (NCT03670953) show that a new formulation of extended-release carbidopa (CD)/levodopa (LD) (IPX-203; Amneal, Bridgewater, NJ) improved motor fluctuations of Parkinson disease (PD) compared with an immediate-r
- Expanding Detection and Increasing Community Education and Services for Alzheimer Diseasehttps://practicalneurology.com/news/expanding-detection-and-increasing-community-education-and-services-for-alzheimer-disease/2469599/A research collaboration (Hackensack Meridian Health and Eisai Inc.) to help address substantial unmet needs of individuals with Alzheimer disease (AD) has been initiated. This collaboration will focus specifically on mild cognitive impairment (MCI). "We are proud to join forces wi