Showing 1321-1330 of 1697 results for "".
- Significant Treatment Gaps Found in People Diagnosed with Chorea Associated with Huntington Diseasehttps://practicalneurology.com/news/significant-treatment-gaps-found-in-people-diagnosed-with-chorea-associated-with-huntington-disease/2473811/Less than 40% of people diagnosed with chorea associated with Huntington disease (HD) received treatment, according to findings of a large observational study published in Neurology and Therapy. In addition, only ~50% of treated patients received first-line monotherapy with the vesicular
- Novel Treatment Approved for NF1-Associated Symptomatic Plexiform Neurofibromashttps://practicalneurology.com/news/new-treatment-approved-for-nf1-associated-symptomatic-plexiform-neurofibromas/2473785/The Food and Drug Administration (FDA) has approved Gomekli (mirdametinib; SpringWorks Therapeutics, Stamford, CN) for the treatment of neurofibromatosis type 1 (NF1)–associated symptomatic plexiform neurofibromas (PNs) not amenable to complete resection in adults and pediatric patients age
- Investigational Therapy Associated with Reduced Infarct Growth in Individuals with Acute Ischemic Strokehttps://practicalneurology.com/news/investigational-therapy-associated-with-reduced-infarct-growth-in-individuals-with-acute-ischemic-stroke/2473782/Treatment with the investigational therapy RNS60 (Revalesio, Tacoma, WA) was associated with a significant reduction in infarct growth and clinically meaningful improvements for individuals with acute ischemic stroke (AIS) treated within 12 hours of symptom onset. These results were presented at
- Guidelines for Evaluating, Diagnosing, and Disclosing Dementia Published by Alzheimer’s Associationhttps://practicalneurology.com/news/guidelines-for-evaluating-diagnosing-and-disclosing-dementia-published-by-alzheimers-association/2470946/The Diagnostic Evaluation, Testing, Counseling, and Disclosure Clinical Practice Guideline (DETeCD-ADRD CPG) Workgroup, convened and funded by the Alzheimer’s Association, has developed new recommendations for clinicians to use when evaluating patients with possible Alzheimer disease (AD) o
- NFL Players Wear Cleats to Support Muscular Dystrophy Associationhttps://practicalneurology.com/news/the-muscular-dystrophy-society-represented-in-the-nfls-my-cause-my-cleats-campaign/2470660/During the “My Cause My Cleats” campaign, which took place during the first 2 weeks of December, several National Football League (NFL) players wore custom-designed cleats to support causes important to them. Nyheim Hines, 2024 Muscular Dystrophy Association (M
- Updated World Medical Association Declaration of Helsinki for Medical Research Ethics Releasedhttps://practicalneurology.com/news/updated-world-medical-association-declaration-of-helsinki-for-medical-research-ethics-released/2470621/The World Medical Association (WMA) has released a revised version of the Declaration of Helsinki, the globally recognized ethical framework for medical research involving human participants. Ratified at the WMA's General Assembly in Helsinki on October 19, 2024, the updated declaration addre
- Experimental Combo Treatment Reduced Alzheimer Disease-Associated Agitationhttps://practicalneurology.com/news/experimental-combo-treatment-reduced-alzheimer-disease-associated-agitation/2470535/Results of the ACCORD (NCT04797715) clinical trial presented at the 2024 meeting of the Alzheimer’s Association International Conference (AAIC) demonstrated that AXS-05 (dextromethorphan-bupropion; Axsome Therapeutics, New York, NY) treatment reduced agitation symptom relapse and was well-t
- Investigational Intradiscal Injection Improved Pain Associated with Lumbar Disc Herniationhttps://practicalneurology.com/news/investigational-intradiscal-injection-improved-pain-associated-with-lumbar-disc-herniation/2470528/People treated with experimental product SI-6603 (condoliase; Ferring Pharmaceuticals, Parsippany, NJ; Seikagaku, Tokyo, Japan) by a single intradiscal injection showed improvements in the radicular leg pain associated with their lumbar disc herniation (LDH). Early response data from a phase 3 st
- Antipsychotic Use Associated with Multiple Adverse Outcomes in Dementia Patientshttps://practicalneurology.com/news/antipsychotic-use-associated-with-multiple-adverse-outcomes-in-dementia-patients/2470475/Antipsychotic use in adults with dementia was associated with increased risks of stroke, venous thromboembolism, myocardial infarction, heart failure, fracture, pneumonia, and acute kidney injury, according to study results published in The BMJ. Previous studies established increased ris
- Meta-Analysis Identifies Association Between Personality Traits and Dementia Riskhttps://practicalneurology.com/news/meta-analysis-identifies-association-between-personality-traits-and-dementia-risk/2470364/Specific personality traits, including neuroticism, negative affect, low conscientiousness, and low extraversion, were associated with an increased risk for a dementia diagnosis, according to research published in Alzheimer’s & Dementia. Conversely, positive affect and higher c