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05.01.19

Young Blood Plasma for Parkinson's Disease


Results of a clinical trial that administered blood plasma from donors, age 18 to 25 years, into individuals with Parkinson's disease resulted in significant improvements in neurologic assessments.

After 3 months, patients showed improvements in motor examinations (19.2%); mentation, behavior, and mood (12.9%); activities of daily living (7.9%); and complications from therapy (50%). Symptoms including dyskinesia and changes in facial expression, speech, handwriting, rigidity, and falling all showed improvement directly attributable to the young plasma. 

The randomized, double-blind, placebo-controlled trial evaluated the efficacy of the plasma (NuPlasma young Fresh Frozen Plasma; NuPlasma, San Marcos, TX) in 19 patients (9 were given young plasma; 10 were given placebo). Patients were intravenously administered 25 mL/kg of the plasma in 2 doses over 3 days.The investigation continued to the point at which the plasma was no longer in circulation, yet continued to show a residual benefit.

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Hans D. Katzberg, MD, MSc, FRCPC; and Hamid Sadeghian, MD, FRCPC