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Neuromuscular

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Muscle Cramps

Reliable and validated outcome measures and new treatments are needed.

Hans D. Katzberg, MD, MSc, FRCPC; and Hamid Sadeghian, MD, FRCPC

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Differential Diagnosis of Distal Myopathies

The era of clinical molecular genetics has refined diagnosis and will hopefully lead to disease-modifying treatments.

Kevin J. Felice, DO

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Noninflammatory Myopathies

As genetic diagnosis increases, noninflammatory myopathies are being seen more in clinical practice.

Yessar Hussain, MD; Krishna Pokala, MD; and Nancy Kuo, MS, MD

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Sporadic Inclusion Body Myositis

An update on pathophysiology with diagnostic and treatment implications.

Matthew Varon, MD; and Pedro M. Machado, MD, PhD

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Congenital Myasthenic Syndrome Treatment

Heterogeneity makes diagnosis and treatment challenging.

Stanley Jones P. Iyadurai, MD, PhD, FAAN

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Spinal Muscular Atrophy

A devastating disease now has 2 approved breakthrough treatments available.

Wijdan Rai, MD; and Bakri Elsheikh, MBBS

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Myasthenia Gravis Treatment

Both symptomatic and maintenance treatments are available.

Thy Nguyen, MD; and Cecile L. Phan, MD

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Amyotrophic Lateral Sclerosis

Integrated care provides the best quality of life.

Jonathan R. Brent, MD, PhD; and Senda Ajroud-Driss, MD

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Utility of Skin Biopsy in Neuromuscular Disease

Intraepidermal nerve fiber density finding can help diagnose small fiber neuropathy.

David S. Saperstein, MD

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HyperCKemia

Evaluation for elevated creatine kinase is a required skill for neurologists.

Nicholas J. Silvestri, MD; and Gil I. Wolfe, MD

Cover Focus

Genetic Testing in Neuromuscular Disorders

Understanding ordering and interpretation of genetic tests is paramount for clinical management.

James P. Orengo, MD, PhD; and David R. Murdock, MD

Guest Medical Editor's Page

Neuromuscular Disease: Dynamic Progress at Work

With 7 new treatments in 5 years, including some of the first approved gene therapies, the field of neuromuscular disorders is making rapid dynamic progress.

Aziz Shaibani, MD

Columns

Neuromuscular Notes: Autoantibodies in Immune Myopathies

Antibody testing results provide clinically useful information.

Emer R. McGrath, MB, PhD

Columns

Neuromuscular Notes: Genetics of Amyotrophic Lateral Sclerosis

Genetic discovery and the promise of gene therapy create hope for effective treatments and eventual prevention.

Katharine Nicholson, MD

Case Report

Case Report: Cyclophosphamide as Rescue Agent in Myasthenic Crisis

When patients are refractory to first-line treatments for myasthenic crisis, cyclophosphamide may have benefits and warrants further study.

Daniel L. Menkes, MD; and Amanda E. Simon, BS


Guest Medical Editor's Page

The Importance of Sleep

Sleep has a critical role in brain health and is an essential part of improving neurologic care for all of our patients.

Logan Schneider, MD

Columns

Hometown Highlights: Congenital Myasthenic Syndromes

With careful diagnosis, treatment can improve symptoms of congenital myasthenic syndromes.

Andrew G. Engel, MD

Special Report

2018 Drug and Device Approvals for Neurology

Spotlight Topic: Neuropsychiatry

Cognitive Complaints and Neuropsychologic Testing

When should neuropsychologic tests be ordered and what questions should testing answer?

Nabil Ali, MD; Laura M. Clark, PhD, ABPP; and Kendra Corning, PsyD, HSPP

Healthy Cognitive Aging

There are evidence-based tools for staying sharp throughout the lifespan.

Brian K. Lebowitz, PhD, ABPP-CN; Elizabeth Londen, PhD; and Thomas Preston, PhD, ABPP-CN

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