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MS Minute: Ibudilast image

Columns

MS Minute: Ibudilast

Ibudilast is a phosphodiesterase inhibitor that has shown some benefit for progressive multiple sclerosis in a phase 2 trial.

Abdul R. Alchaki, MD; and Andrew D. Goodman, MD

Susac Syndrome image

Cover Focus

Susac Syndrome

A triad of encephalopathy, branch retinal artery occlusions, and sensorineural hearing loss.

Ilka Kleffner, MD; Catharina C. Gross, PhD; Marius Ringelstein, MD; Jörg Rehrmann, MD; Markus Kraemer, MD; and Jan Dörr, MD

2019 Drug and Device Approvals in Neurology image

Special Report

2019 Drug and Device Approvals in Neurology

Challenge Case Report: Aseptic Meningitis Worsening With Treatment image

Case Reports

Challenge Case Report: Aseptic Meningitis Worsening With Treatment

Diagnosis should be re-evaluated when clinical situations change.

David Horvat, MD; Jack Lovell, DO; and Glen Cook Jr, MD

Case Report: Seizure, Fever, Hallucinations, & Vision Loss image

Case Reports

Case Report: Seizure, Fever, Hallucinations, & Vision Loss

A circuitous route to dual diagnoses.

Elizabeth Carroll, MD; Asya I. Wallach, MD; Arielle Kurzweil, MD; Steven Frucht, MD; Thomas Berk, MD; Michael Boffa, MD; and Ilya Kister, MD

MS Minute: Oral Therapies for MS image

Columns

MS Minute: Oral Therapies for MS

The advent of oral therapies has ushered in a new phase of disease-modifying treatments.

Neeta Garg, MD; Micheline McCarthy, MD, PhD; and Ameeta Karmarkar, MD

Case Report: Hemiparkinsonism in a Patient With Multiple Sclerosis image

Case Report

Case Report: Hemiparkinsonism in a Patient With Multiple Sclerosis

In this case, there was a causal relationship between comorbid diseases.

Andrea P. Lee, MD; Giulietta M. Riboldi, MD; Ilya Kister, MD; Jonathan E. Howard, MD; and Ritesh A. Ramdhani, MD

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Special Report

Dizziness and Vertigo

Part 1: Untangling the complexity of dizziness and vertigo requires a careful history.

Daniel R. Gold, DO; and Ari A. Shemesh, MD

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Guest Medical Editor's Page

The Importance of Sleep

Sleep has a critical role in brain health and is an essential part of improving neurologic care for all of our patients.

Logan Schneider, MD

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Multiple Sclerosis Minute: Telemedicine and Multiple Sclerosis

Telemedicine is acceptable to patients and clinicians in the continuum of clinic-to-in-home care and reduces barriers to care.

Valerie J. Block, DPTSc, PT; and Riley Bove, MD, MMSc

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Emerging Therapies for Progressive Multiple Sclerosis

A number of agents with putative neuroprotective effects have shown promise in recent clinical trials.

Matthew Tremblay, MD, PhD

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Pediatric-Onset Multiple Sclerosis

Information from clinical trials in children with MS is furthering understanding and improving treatment options for this rare presentation.

Brenda L. Banwell, MD; and Duriel I. Hardy, MD

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Immunopathogenesis of Multiple Sclerosis

Disruption of immune tolerance, inflammation, and blood-brain–barrier breach lead to demyelination and axonal injury.

Neeta Garg, MD; Ye Hu, MD; and Kottil W. Rammohan, MD

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Neuromyelitis Optica Spectrum Disorders

It is critical to maintain a high index of suspicion for these conditions when evaluating a patient with demyelination to avoid delays in treatment.

Michael J. Bradshaw, MD; and Dorlan Kimbrough, MD

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POINT-COUNTERPOINT: Natalizumab Extended-Interval Dosing

Optimism vs caution for using extended-interval dosing to prevent progressive multifocal leukoencephalopathy.

David B. Clifford, MD; and John F. Foley, MD


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Cover Focus: Multiple Sclerosis & Demyelinating Disorders

Multiple Sclerosis Misdiagnosis

Accurate diagnosis requires correspondence to typical clinical syndromes, correct interpretation of radiologic and CSF data, and thorough evaluation for mimics.

Alexandra Galati, MD; and Marwa Kaisey, MD

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Maintaining Ambulation

Physical therapy, exercise, physical activity, and medications adapted to individual needs can all help maintain the ability to walk.

Michelle H. Cameron, MD, PT, MCR; and Ylva E. Nilsagård, PT, PhD

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Guest Medical Editor's Page

A Coming of Age for Neuroimmunology

Increasingly complex diagnostics and highly effective disease-modifying therapy come with challenges in clinical decision making.

Aaron M. Carlson, MD

Case Report: Longitudinally Extensive Transverse Myelitis image

Case Report

Case Report: Longitudinally Extensive Transverse Myelitis

The borderline of neuromyelitis optica and systemic lupus erythematosus.

Ylec Mariana Cardenas, MD; Lakshmi Leishangthem, MD; Aparna Prabhu, MD; David Roby, MD; Pooja SirDeshpande, MD; and Saman Zafar, MD

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MS Minute: Introducing The New Editors

Our new editors continue their professional collaboration to help advance care of patients with MS.

Barbara S. Giesser, MD, FAAN, FANA; and Lawrence Samkoff, MD, FAAN

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