Weakness and Atrophy of Right Hand Muscles in A 47-year-old Man

A 47-year-old man presents with a 13-year history of weakness and atrophy of the right hand muscles. Thoracic outlet syndrome surgery did not help. CK level and CSF examination were normal. Cervical MRI was normal. NCS showed no conduction block. The CMAPs of the right median and ulnar nerves were reduced. Sensory responses were normal. EMG revealed diffuse chronic denervation of the right arm muscles.

At what level is the lesion likely located?
1. Motor neurons
2. Motor nerves
3. Brachial plexus
4. Axons
5. Myelin

 
 

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About Practical Neurology

Launched in January 2002, Practical Neurology strives to enhance quality of care and improve the daily operation of neurology practices. Each month, our experts explain the real-world significance of recent advances in neurologic science and offer step-by-step advice on how to overcome the clinical and business challenges neurologists face. Our straightforward, how-to articles give neurologists tools they can put into practice right away.

 
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