Headache & Pain

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FDA Approves Galcanezumab for Prevention of Migraine

Friday, September 28, 2018—The Food and Drug Administration (FDA) has approved galcanezumab-glnm (Emgality; Lilly, Indianapolis, IN) for the prevention of migraine in adults. Galcanezumab is available a…

Fremanezumab-vfrm Approved for Prevention of Migraine

Monday, September 17, 2018—The Food and Drug Administration (FDA) has approved fremanezumab-vfrm (Ajovy; Teva Pharmaceutical Industries, Jerusalem, Israel) for prevention of migraine in adults. Fre…

New Investigational Intranasal CGRP-Antagonist for Treatment of Migraine

Wednesday, September 12, 2018—An investigational drug application has been filed with the Food and Drug Administration (FDA) for BHV-3500 (Biohaven, New Haven, CT). This new compound is the first intranasa…

Phase 3 Results for Rimegepant for Treatment of Migraine Being Presented

Thursday, September 06, 2018—Data from 2 phase 3 pivotal trials of rimegepant (Biohaven, New Haven, CT) for treatment of patients with migraine will be presented at the 17th Biennial Migraine Trust Intern…

Lower Extremity Radicular Pain Relieved With Tetrahydrocannabinol

Wednesday, September 05, 2018—In a small (n = 17 men), double-blind, placebo-controlled study using a counterbalanced within-subjects design, treatment of patients with chronic neuropathic pain with d…

NIH Announces Launch of Studies to Understand Acute to Chronic Pain Transition

Tuesday, August 28, 2018—The National Institutes of Health (NIH) has launched a new program to study how acute pain transitions into chronic pain and to identify biologic characteristics underlying th…

Intrathecal Baclofen More Effective Than Oral Medication for Treating Pain in Patients With Poststroke Spasticity

Thursday, August 16, 2018—Results from the SISTERS trial (NCT01032239) show that intrathecal administration (ITB Therapy; Medtronic, Dublin, Ireland) of baclofen (Lioresal Intrathecal; Saol Therapeutic…

Breaching the Blood-Brain Barrier: A Potential New Treatment Modality

Monday, July 30, 2018—In a small, yet groundbreaking, clinical trial, MR-guided focused ultrasound (MRgFUS) (ExablateNeuro; Insightec, Miami FL) was used to open the blood-brain barrier (BBB) safel…


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.