Headache & Pain

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Headache Horizons: Migraine Work in Translation

With Richard B. Lipton, MD

February 2019—From discovery of CGRP to the monoclonal antibodies of today and -gepants of tomorrow, basic science has been translated to clinical progress over just 3 decades.

Sumatriptan Nasal Spray Approved for Acute Migraine Treatment

Monday, January 28, 2019—The Food and Drug Administration has approved sumatriptan nasal spray 10mg (Tosymra; Promius Pharma, Princeton, NJ) for acute treatment of migraine with or without aura in adu…

Wireless Spinal Cord Stimulator Provides Relief from Chronic Pain

Friday, January 18, 2019—Clinical trial results showed that the world’s first wireless, fully programmable neuromodulation system (Freedom SCS System; Stimwave Technologies, Pompano Beach, FL) p…

Registry for Peripheral Nerve Stimulation for Pain Management Is Launched

Wednesday, January 16, 2019—The first registry related to peripheral nerve stimulation (PNS) for pain management is enrolling patients. The registry will collect long-term clinical data with the goal of …

Federal Supply Schedule Adds External Vagus Nerve Stimulator for Headache Prevention and Treatment

Tuesday, January 08, 2019—A noninvasive vagus nerve stimulation (nVNS) device (gammaCore; electroCore, Basking Ridge, NJU) has been award a 5-year Federal Supply Schedule medical equipment and supply c…

Phase 3 Trial of Dioscorea japonica Extracts To Be Initiated for Treatment of Pain From Diabetic Neuropathy

Tuesday, January 08, 2019—The planned initiation of a phase 3 double-blind, placebo controlled, 12-week study of Dioscorea japonica extracts (NB-01; Neurobo, Boston, MA) for pain relief in pa…

2018 Drug and Device Approvals for Neurology

January 2019—HEADACHE & PAIN Noninvasive Vagus Nerve Stimulation (Gammacore; electroCore, Basking Ridge, NJ) Cleared: November 28, 2018 and January 29, 2018 Indications: adjun…

Hometown Highlights: CGRP-Related Treatments for Headache

With Stephen D. Silberstein, MD

January 2019— What Is Most Significant About These New Treatments? For the first time, we’ve developed a treatment for migraine based on what causes migraine. We had the concep…


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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.