November/December 2013—In 1672, Thomas Willis provided the first description of chronic migraine (CM) when he reported the
case of the philosopher, Anne, Viscountess Conway, who was also treated by William Harvey and
Robert Boyle without success.1-4 Has our treatment of chronic migraine since improved?
January/February 2013—New evidence suggests that opioid overuse headache may involve activation of glial cells, in particular astrocytes and microglia, which creates a pro-inflammatory state that leads to pain facilitation.
Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.