Headache & Pain

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Intrathecal Baclofen More Effective Than Oral Medication for Treating Pain in Patients With Poststroke Spasticity

Thursday, August 16, 2018—Results from the SISTERS trial (NCT01032239) show that intrathecal administration (ITB Therapy; Medtronic, Dublin, Ireland) of baclofen (Lioresal Intrathecal; Saol Therapeutic…

Breaching the Blood-Brain Barrier: A Potential New Treatment Modality

Monday, July 30, 2018—In a small, yet groundbreaking, clinical trial, MR-guided focused ultrasound (MRgFUS) (ExablateNeuro; Insightec, Miami FL) was used to open the blood-brain barrier (BBB) safel…

Going Off the Grid to a Noninsurance-Based Practice

Peter McAllister, MD; and Angelo Termine, MSM, MBA

July/August 2018—A personal journey of surviving and thriving.

What Do Clinicians Need to Know About CGRP-Related Headache Treatments?

July/August 2018—Answers from neurologists attending the American Headache Society 60th Annual Meeting in San Francisco, California, June 28-July 1, 2018.

Rimegepant Provides Freedom From Pain and Other Symptoms in Phase 3 Clinical Trials

Tuesday, July 03, 2018—Expanded data from 2 randomized, pivotal phase 3 clinical trials of rimegepant (Biohaven, New Haven, CT), a small molecule calcitonin gene-related peptide (CGRP) receptor anta…

Addressing the High Impact of Migraine at Work

Saturday, June 30, 2018—Initial findings from a large global migraine patient survey involving >11,000 people from 31 countries show migraine is associated with overall work and activity impairmen…

Ketamine Guidelines for Acute Pain Management Established and Released for the First Time

Friday, June 15, 2018—Intravenous (IV) ketamine has been used to treat acute pain in multiple conditions including as a stand-alone treatment, and as an adjunct to opioids. Ketamine is being used i…

Atogepant Demonstrates Efficacy and Safety for Prevention of Episodic Migraine

Wednesday, June 13, 2018—In a phase 2b/3 clinical trial (CGP-MD-01) of the orally administered calcitonin gene-related peptide receptor (CGRP) antagonist, atogepant (Allergan, Ireland), all primary en…


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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.