Latest News - Neuromuscular

Thursday, January 17, 2019

Neuromuscular Community Survey Identifies Key Issues

The Muscular Dystrophy Association (MDA) has announced results of a landmark survey that asked more than 3,000 people affected by neuromuscular disease (NMD) about their key areas of concern and possi…

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Tuesday, January 08, 2019

Phase 3 Trial of Dioscorea japonica Extracts To Be Initiated for Treatment of Pain From Diabetic Neuropathy

The planned initiation of a phase 3 double-blind, placebo controlled, 12-week study of Dioscorea japonica extracts (NB-01; Neurobo, Boston, MA) for pain relief in patients with diabetic neur…

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Thursday, January 03, 2019

American Academy of Neurology Call for Uniformity in Brain Death Standards

Noting that only 1 state, Nevada, has adopted legislation requiring use of medically accepted guidelines for determining brain death, the American Academy of Neurology (AAN) is calling for action on t…

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Friday, December 28, 2018

Reliability of Ultrasound Measurements in Patients with Amyotrophic Lateral Sclerosis

In a study published in the journal Muscle & Nerve, researchers suggest diagnostic ultrasound may provide a reliable biomarker for amyotrophic lateral sclerosis (ALS). This study used ultraso…

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Wednesday, December 05, 2018

FDA Accepts Application for Genetic Treatment of Spinal Muscular Atrophy Type 1

The Food and Drug Administration (FDA) has accepted the Biologics License Application for onasemnogene abeparvovec-xxxx (AVXS-101, Zolgensma; AveXis, Bannockburn, Illinois), an investigational ge…

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Tuesday, December 04, 2018

Dystonia and Spasticity Patients May Become Immune to Toxin Treatment

People with dystonia or spasticity can get relief from botulinum toxin type A, but a new study published online in Neurology shows that 15% of people treated with the toxin can develop an im…

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Monday, December 03, 2018

FDA Approves Amifampridine for Lambert-Eaton Myasthenic Syndrome

The FDA has approved amifampridine (Firdapse, Catalyst Pharmaceuticals, Coral Gables, FL) tablets for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults. This is the first FDA approva…

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Wednesday, November 28, 2018

Biases in Dementia Screening Tools

Brief cognitive tests are useful screening tools for dementia in the primary care setting; however, a study published in the journal Neurology Clinical Practice shows that 3 of the most comm…

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Tuesday, November 13, 2018

Possible Therapy for Polio-Like Illness Is Not Effective

In new research on a potential treatment for acute flaccid myelitis, the antidepressant fluoxetine showed no efficacy. The study, published in the November 9, 2018 online issue of Neurology, …

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Tuesday, November 06, 2018

Neurostimulation-Enabled Prosthetic Hand Delivers Sensory Input

In a first-in-human trial of the neural-enabled prosthetic hand (NEPH) system, promising results have been announced by the Florida Interenational University, investigator Ranu Jung, and the Adaptive …

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Tuesday, October 16, 2018

Phase 3 Results for Eculizumab for Treatment of Patients with Myasthenia Gravis

At the American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) in Washington, DC, October 10-12, results were presented from the phase 3 REGAIN trial (NCT01997229) and the REGAIN …

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Monday, October 15, 2018

AANEM Meeting Highlights Precision Medicine, Access to Care, and Technology for Neuromuscular Diseases

The American Association of Neuromuscular and Electrodiagnostic Medicine 34th Annual Meeting was held in Washington, DC October 10-12. The theme of the meeting was precision medicine, which included s…

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Friday, October 12, 2018

Patisiran and Inotersen Continue to Show Efficacy and Safety in Open-Label and Expanded-Access Trials for Patients With Hereditary Transthyretin-Mediated Amyloidosis

Results from an open-label extension of the multi-center, randomized, double-blind phase 3 APOLLO study (NCT01960348) of patisiran (Onpattro; Alnylam, Cambridge, MA) and from the NEURO-TTR study (NCT0…

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Friday, October 12, 2018

Thymectomy May be Effective Only For Some Forms of Myasthenia Gravis

Although randomized trials demonstrate that treatment with thymectomy has benefits for patients with nonthymomatous antiacetylcholine receptor (AChR) antibody positive generalized myasthenia gravis (M…

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Wednesday, October 10, 2018

Muscular Dystrophy Association Funds $9.9 Million in Research Grants

The Muscular Dystrophy Association (MDA) has announced a new round of grant funding that includes second-generation precision medicine treatments, disease-specific research networks, analysis of large…

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