Latest News - Sleep

Tuesday, September 25, 2018

Patients With Epilepsy and Obstructive Sleep Apnea Have More Frequent Seizures

A pilot study of 49 adult patients with refractory focal, generalized, or unclassified epilepsy syndromes enrolled prospectively found those with probable obstructive sleep apnea (OSA) had more freque…

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Tuesday, September 25, 2018

Smart Phone Tests May Distinguish Parkinson’s from Idiopathic REM Sleep Behavior Disorder

In a paper published in Neurology, researchers report that consumer-grade smartphones can be used to accurately identify patients with Parkinson’s disease (PD) versus those with idiopathic REM s…

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Tuesday, September 11, 2018

Pitolisant for Treatment of Patients with Narcolepsy has Long-Term Safety, Tolerability, and Durability of Effect

Long-term data for pitolisant (Harmony Biosciences, Plymouth Meeting PA), an investigational treatment for excessive daytime sleepiness (EDS) and cataplexy in patients with narcolepsy, were presented …

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Monday, July 30, 2018

Breaching the Blood-Brain Barrier: A Potential New Treatment Modality

In a small, yet groundbreaking, clinical trial, MR-guided focused ultrasound (MRgFUS) (ExablateNeuro; Insightec, Miami FL) was used to open the blood-brain barrier (BBB) safely in 5 persons with mild-…

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Thursday, July 19, 2018

Potential Source for New Biomarkers in Sleep Disorders

A study just published in the journal PLOS One shows that there are circadian molecules in saliva that are disrupted in children with sleep disorders.  These results advance our understanding of …

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Tuesday, June 05, 2018

Patients Treated With Lemborexant Awake and Return to Sleep Safely Without Fall Risk

In results presented today at the Associated Professional Sleep Societies meeting (SLEEP 2018, Baltimore, MD) it was shown that patients treated with lemborexant (Eisai, Woodcliff Lake, NJ and Purdue …

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Tuesday, June 05, 2018

American Academy of Sleep Medicine Issues Advisory: Insufficient Sleep May Increase Risk for Alzheimer’s Disease

The American Academy of Sleep Medicine (AASM) has issued a health advisory warning that insufficient or poor sleep may increase the risk of developing Alzheimer’s disease (AD). The AASM believes…

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Monday, June 04, 2018

Excessive Sleepiness Impacts More Than Quality of Life: More Awareness Needed

Results from a survey of sleep specialists suggest there is a need for greater awareness of the neurologic effects of excessive sleepiness (ES), including neuronal injury and neurocognitive impairment…

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Monday, May 21, 2018

FDA Grants Breakthrough and Fast-Track Designations to Pitolisant for Treatment of Patients With Narcolepsy

The Food and Drug Administration (FDA) has granted fast-track and breakthrough therapy designations to the investigational therapy pitolisant (Harmony Biosciences, Plymouth Meeting, PA) for the treatm…

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Monday, January 08, 2018

Guidance for the Use of Opioids in the Treatment of Refractory Restless Leg Syndrome

On January 8, 2018, Mayo Clinic Proceedings published an article on appropriate use of opioids for treating refractory restless legs syndrome (RLS) by members of the Scientific and Medical Advisory Bo…

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Thursday, July 06, 2017

Sleep Disturbances Linked to Alzheimer’s Disease

Poor sleep may be a sign that otherwise healthy individuals may have an increased risk of developing Alzheimer’s disease later in life over those who do not have sleep problems, according to a s…

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Thursday, January 26, 2017

Investigational Narcolepsy Agent Found Effective for Severely Affected Patients with Cataplexy in Phase 3 Study

Results from a phase 3 controlled trial show that pitolisant (Wakix, Bioproject Pharma) may be efficacious in severely affected narcoleptic patients with cataplexy. Pitolisant is a highly-selective hi…

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