Latest News - Research and Publications

Wednesday, June 14, 2017 | Movement Disorders, Phase 3/4 Trials, Research and Publications

Phase 3 Results Published for Investigational Levodopa-Induced Dyskinesia Treatment

Results from the Phase 3 EASE LID clinical trial, published online in JAMA Neurology, show that the investigational ADS-5102 (amantadine, Adamas Pharmaceuticals) reduces levodopa-induced dyskinesia (L…

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Tuesday, June 13, 2017 | Pain & Headache, Phase 3/4 Trials, Research and Publications

AHS 2017: Amgen’s CGRP Inhibitor Reduces Migraine Days

New Phase 2 data show that Amgen’s investigational investigational CGRP inhibitor erenumab is effective at preventing migraine in patients experiencing 15 or more migraine days per month. In a s…

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Friday, June 09, 2017 | Movement Disorders, Research and Publications

Anti-Alpha-Synuclein Antibody Shows Early Potential as Parkinson’s DMT

PRX002, an investigational monoclonal antibody, may inhibit cell-to-cell transmission of alpha-synuclein and modify disease progression in Parkinson’s disease (PD), according to a study presente…

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Thursday, June 08, 2017 | Pain & Headache, Phase 3/4 Trials, Research and Publications

AHS 2017 Meeting: Prochlorperazine More Effective than Hydromorphone for Acute Migraine

A new comparative study presented at the American Headache Society Annual Meeting in Boston shows that that, in patients who visit the emergency department for acute migraine treatment, prochorperazin…

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Thursday, June 08, 2017 | Pain & Headache, Phase 3/4 Trials, Research and Publications

AHS 2017 Meeting: Non-Invasive Medical Devices Show Promise for Severe Headaches

Results from studies presented at the American Headache Society Annual Meeting in Boston suggest that non-invasive medical devices offer effective interventions for individuals with migraine. …

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Wednesday, June 07, 2017 | Movement Disorders, Research and Publications

Smartphone Sensor Data Offer Insights Into Daily Functioning in Patients with Parkinson’s Disease

Smartphones are a valuable resource in gaining mobility data in patients with Parkinson’s disease, according to new research presented at the 21st International Congress of Parkinson’s Dis…

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Thursday, June 01, 2017 | Pain & Headache, Phase 3/4 Trials, Research and Publications

Teva’s Fremanezumab Reduces Monthly Headache Days in Phase 3 Chronic Migraine Study

    Results from the Phase 3 HALO study suggest that fremanezumab (Teva Pharmaceuticals) reduces the number of monthly headache days in patients with chronic migraine. Fremanezumab is …

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Tuesday, May 30, 2017 | Dementia & Cognitive Disorders, Movement Disorders, Research and Publications

Neurodegenerative Diseases Linked by Abnormal Proteins Causing Similar Damage to Brain Cells

Abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease share a similar ability to cause damage when they invade brain cells, according to recently pu…

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Friday, May 26, 2017 | Epilepsy & Seizure Disorders, Phase 3/4 Trials, Research and Publications

NEJM Publishes Phase 3 Data for Epidiolex in Dravet Syndrome as Manufacturer Eyes Mid-2017 NDA Submission

The New England Journal of Medicine has published results from a Phase 3 study showing that Epidiolex (cannabidiol, GW Pharmaceuticals) reduces monthly convulsive seizure frequency compared to placebo…

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Tuesday, May 23, 2017 | Neuromuscular & Immune Disorders, Phase 3/4 Trials, Research and Publications

Celgene’s Investigational MS Agent Reduces Annual Relapse Rate but Falls Short of Disability Endpoint in Phase 3 Trial

New Phase 3 findings suggest that Celgene’s investigational ozanimod for relapsing multiple sclerosis (MS) reduces annualized relapse rate in a clinically meaningful way but does not significant…

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Friday, May 19, 2017 | Pain & Headache, Research and Publications

Migraine Prevalence Higher in Collegiate Athletes, New Study Finds

New findings suggest that collegiate athletes have an increased prevalence of migraines, with female athletes being particularly affected. In a retrospective cross-section survey, researchers evaluate…

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Tuesday, May 16, 2017 | Product Launches and Updates, Research and Publications, Stroke & Cerebrovascular

Endovascular Intervention Found Effective for "Late Window" Stroke Patients: DAWN Trial Analysis

The window for reducing disability and improving functional independence in stroke patients receiving endovascular therapy could extend as far as 24 hours, according to preliminary results from the DA…

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Friday, May 12, 2017 | Research and Publications, Stroke & Cerebrovascular

Elevated B2M Levels Tied to Ischemic Stroke Risk in Women

β2-microglobulin (B2M) levels may be an indicator of ischemic stroke risk in women, according to new findings published in Neurology (May 10). Investigators performed a nested case-control study …

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Friday, May 12, 2017 | Pain & Headache, Phase 3/4 Trials, Research and Publications

Lilly’s Investigational Monoclonal Antibody for Migraine Scores Positive Phase 3 Results

New Phase 3 data suggest that Eli Lilly’s investigational monoclonal antibody galcanezumab may significantly reduce the number of monthly migraine headache days. In the EVOLVE-1 study, pati…

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Friday, May 05, 2017 | FDA Approval/Clearance, Neuromuscular & Immune Disorders, Phase 3/4 Trials, Research and Publications

FDA Greenlights First New Treatment for ALS in More than Two Decades

The FDA has approved Radicava (edaravone, MT Pharma), as an intravenous infusion treatment for amyotrophic lateral sclerosis (ALS). Radicava is the first treatment approved for the treatment of A…

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