High Levels of Aluminum Found in Brain Tissue of Individuals with Familial Alzheimer’s Disease

Thursday, January 12, 2017 | Dementia & Cognitive Disorders , Research and Publications


A British study has found extremely high levels of aluminum in the tissue of brains of individuals with familial Alzheimer’s disease. Using fluorescence microscopy to identify aluminum, investigators looked at brain tissue from 12 donors of those who were genetically predisposed to Alzheimer's, finding in excess of 10 μg/g tissue dry wt, levels that are higher than almost all previous measurements of brain aluminum. Cases of sporadic Alzheimer's disease have previously been linked to unusually high exposure to aluminum through the environment or workplace. However, these earlier studies have failed to explain the causes of Alzheimer's in those genetically predisposed to the disease. The results were published in the Journal of Trace Elements in Medicine and Biology.

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