Movement Disorders

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Alpha-Synuclein: A Therapeutic Target and Potential Biomarker in Parkinson’s Disease

Rachel Dolhun, MD

November/December 2016—The story of alpha-synuclein and Parkinson’s disease (PD) began just two decades ago, when relatively newer genetic techniques at that time identified a single mutation …

Diagnosis and Management of Neurodegenerative Atypical Parkinsonism

Rachel Dolhun, MD

June 2016—"Parkinsonism” and “parkinsonian” are terms broadly used to describe the motor features (i.e., bradykinesia, rigidity, resting tremor) typically associa…

Special Report: AAN Annual Meeting: Video Coverage, Study Highlights, and More

May 2016— Last month, thousands of members of the international neurology community convened in Vancouver for the Annual Meeting of the American Academy of Neurology (AAN). Practical …

SmartCare: How New Technologies Are Changing the Parkinson’s Spectrum

With Ray Dorsey, MD, MBA

April 2016—Over the last half-century, the productivity of the drug development industry has been in steep decline. Pharmaceutical companies are spending more money on the development of…

New and Emerging Therapies in Parkinson’s Disease

Laxman Bahroo, DO, Fahd Amjad, MD, Khashayar Dhastipour, MD, and Fernando Pagan, MD

April 2016—As the therapeutic landscape expands, an increasing range of options and a promising horizon will improve management of motor fluctuations for many patients with Parkinson’s disease.

Deep Brain Stimulation in Parkinson’s Disease: Past, Present, and Future

With Mahlon DeLong, MD

April 2016—Though it has been underutilized over the past two decades, deep brain stimulation is an effective intervention for many individuals with Parkinson’s disease.

Parkinson’s Pathology: Elucidating the Role of LRRK2

With Marco Baptista, PhD

April 2016—Playing a critical role in Parkinson’s disease, LRRK2 offers a potential path toward better understanding and potentially treating the condition.

Innovations in Parkinson’s Disease: Deep Brain Stimulation and Magnetic Resonance-guided Focused Ultrasound

Rachel Dolhun, MD

January/February 2016—Rapid progress in deep brain stimulation and focused ultrasound offer a glimpse of the future of treatment for Parkinson’s disease.


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About Practical Neurology

Launched in January 2002, Practical Neurology strives to enhance quality of care and improve the daily operation of neurology practices. Each month, our experts explain the real-world significance of recent advances in neurologic science and offer step-by-step advice on how to overcome the clinical and business challenges neurologists face. Our straightforward, how-to articles give neurologists tools they can put into practice right away.