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Phase 1 Trial Initiated for Product Candidate CAD-1883, Hoped to Provide Treatment for Spinocerebellar Ataxia and Essential Tremor

Monday, March 12, 2018—Novel therapeutics developer, Cadent Therapeutics (Cambridge, Massachusetts) has initiated a phase 1 clinical trial for product candidate CAD-1883, which is an allosteric modu…

Biosimilar Being Developed for Botox

Thursday, March 01, 2018—In a transatlantic collaboration, Mylan N.V. (Pittsburgh, Pennsylvania) and Revance Therapeutics, Inc. (Hertsfordshire, England) have reached an agreement to collaborate on th…

Kenneth Marek, MD Joins the Michael J. Fox Foundation for Parkinson's Research as Scientific Advisor

Tuesday, February 27, 2018—The Michael J. Fox Foundation for Parkinson's Research (MJFF) announced that Kenneth Marek, MD, has joined the Foundation as Scientific Advisor. In this role, Dr. Mar…

Tears May Contain a Biomarker for Parkinson's Disease

Thursday, February 22, 2018—A preliminary study will be presented at the American Academy of Neurology (AAN) meeting in Los Angeles, April 21-27, that shows there may be a biomarker in tears for Parkinso…

Food and Drug Administration Approves Extended-Release Amantadine for Treatment of Parkinson's Disease and Drug-Induced Extrapyramidal Reactions in Adults

Tuesday, February 20, 2018—The Food and Drug Administration (FDA) approved Osmolex ER (Osmotica Pharmaceuticals; Bridgewater, NJ) an extended-release formulation of amantadine for the treatment of Parki…

Neurocrine Biosciences Receives Guidance from Food and Drug Administration for New Drug Application for Opicapone as Adjunct Therapy to Levodopa in Parkinson's Disease

Wednesday, February 14, 2018—Opicapone, a novel, once-daily, peripherally-acting, highly-selective catechol-o-methyltransferase (COMT) inhibitor that prolongs the effect of levodopa by decreasing the rate…

Alkahest Receives Grant From the The Michael J. Fox Foundation for Parkinson's Research for Clinical Trial of GRF6019

Monday, February 12, 2018—On February 12, 2018, Alkahest, a privately-held clinical-stage company developing treatments for age-related diseases announced that they had received funding from the Michal…

National Institutes of Health Researchers Adapt Test for Early Diagnosis of Parkinson's Disease and Dementia with Lewy Bodies

Friday, February 09, 2018—Acta Neuropathologica Communications published a paper by researchers at the National Institutes of Health (NIH) (Groveman BR, Orrù CD, and Hughson AG, et al. Acta Neur…


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.