Movement Disorders

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Retinal Deposits of Phosphorylated Alpha-Synuclein: A Biomarker for Parkinson’s Disease?

Thursday, May 10, 2018—Analysis of retinas from 19 autopsied subjects, 9 with Parkinson’s disease (PD), and 4 with incidental Lewy body disease, showed accumulation of phosphorylated α…

Amantadine-Extended Release: Different Pharmocokinetics Drive Different Clinical Effects

Tuesday, May 08, 2018—Amantadine-ER (Gocovri; Adamas, Emeryville, CA) is approved by the Food and Drug Administration (FDA) for treatment of dyskinesia in patients with Parkinson’s disease ta…

Nonmotor Symptoms of Parkinson’s Disease Underreported and Undertreated

Monday, May 07, 2018—More than 2 in 3 patients with Parkinson’s disease (PD) or their caregivers affirm the presence of nonmotor symptoms that significantly and negatively affect their quali…

A Breathtaking Evolution of Therapeutic Approaches

Stephen M. Gollomp, MD

May 2018— The recent evolution of therapeutic ap-proaches to movement disorders has been almost breathtaking and a bit disorienting. That is why we thought it was time to dedicate a…

Prodromal and Early Parkinson’s Disease Diagnosis

Sneha Mantri, MD; and James F. Morley, MD, PhD

May 2018—Earlier diagnosis may lead to earlier and more effective treatments.

Pharmaceutical Treatment of Parkinson’s Disease

Laura Buyan-Dent, MD; Teresa Mangin, MD; and Kathleen M. Shannon, MD

May 2018—The best outcomes rely on a handful of medicines and partnership among clinicians, patients, and caregivers.

The Role of Exercise in Treating Parkinson’s Disease

Natalie P. Witek, MD; and Cynthia L. Comella, MD

May 2018—There is growing evidence that high-intensity exercise is neuroprotective.

Surgical Interventions for Parkinson’s Disease

Drew S. Kern, MD, MS; Emily Forbes, DO; and Binit B. Shah, MD

May 2018—Consider surgical interventions when symptoms include motor complications that affect quality of life despite optimized pharmacotherapy.


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.