Epilepsy & Seizures

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SUDEP: Risk Factors and Proposed Mechanisms

Michelle L. Dougherty, MD

July/August 2017—Patients and families deserve information about their risk for SUDEP and steps that can be taken to minimize that risk.

VNS Therapy Approved in Children Ages Four Years and Older with Partial Onset Refractory Seizures

Friday, June 30, 2017—The FDA has approved the VNS Therapy (LivaNova) in patients as young as four years of age with partial onset refractory seizures. Originally approved for patients ages 12…

Low-Dose Fenfluramine Granted Orphan Status for LGS

Tuesday, June 27, 2017—The FDA has granted orphan drug designation to ZX008 (Zogenix), an investigational treatment for Lennox Gastaut Syndrome (LGS). Zogenix will initiate a Phase 3 clinical trial …

American Epilepsy Society Awards Investigators for Early Career Research

Monday, June 12, 2017—The American Epilepsy Society (AES) has awarded 25 early career scientists and clinicians with fellowships or grants to support their work in epilepsy research. The award reci…

NEJM Publishes Phase 3 Data for Epidiolex in Dravet Syndrome as Manufacturer Eyes Mid-2017 NDA Submission

Friday, May 26, 2017—The New England Journal of Medicine has published results from a Phase 3 study showing that Epidiolex (cannabidiol, GW Pharmaceuticals) reduces monthly convulsive seizure freq…

New Data Highlight Efficacy and Safety of Brain Responsive Neuromodulation for Reduction of Seizures

Wednesday, May 03, 2017—Two new studies offer long-term perspective on the efficacy and safety of brain responsive neuromodulation for the reduction of seizures. One study evaluated the effects of Ne…

AAN Unveils New Guideline for SUDEP at Annual Meeting

Tuesday, April 25, 2017—The American Academy of Neurology (AAN) and the American Epilepsy Society (AES) have released a new joint guideline for sudden unexpected death in epilepsy (SUDEP) at the AAN …

The Utility of EEG in Prognosis Post-Cardiac Arrest

Michelle Dougherty, MD

April 2017—EEG findings are helpful at either end of the spectrum, but more research is needed before it can be used more broadly to determine prognosis for patients with cardiac arrest.


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.