Epilepsy & Seizures

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Perampanel Safety, Efficacy, and Predictors of Major Response

Friday, April 27, 2018—Perampanel (FYCOMPA; Eisai, Woodcliff Lake, NJ) is approved for use as monotherapy for treatment of partial-onset seizures (POS) with or without secondarily generalized seizur…

Advisory Committee Supports Approval of Oral Cannabidiol for Dravet Syndrome and Lennox-Gastaut Syndrome

Thursday, April 19, 2018—The Peripheral and Central Nervous System Drugs Advisory Committee of the Food and Drug Administration (FDA) unanimously recommended supporting the approval of the investigati…

Everolimus Approved as Adjunctive Treatment for Tuberous Sclerosis-Associated Partial-Onset Seizures

Wednesday, April 11, 2018—The Food and Drug Administration (FDA) has granted approval for the use of everolimus (Afinitor DISPERZ; Novartis, East Hanover, NJ) to treat tuberous sclerosis complex (TSC)-…

Approval Sought for use of Perampanel in Pediatric Patients With Epilepsy

Friday, March 30, 2018—A supplemental new drug application (sNDA) has been submitted seeking priority review for the use of perampanel (CIII) (FYCOMPA; Eisai Inc, Woodcliff Lake, NJ) for specif…

New Therapeutic Candidates Identified for SCN8A-Related Epilepsy

Monday, March 26, 2018—Caused by a gain-of-function mutation in the SCN8A gene encoding the Nav1.6 sodium channel, SCN8A-related epilepsy is characterized by developmental delay, seizure onset in in…

Seizures and Epilepsy in the Elderly

Rani A. Sarkis, MD, MSC; and Matthew Schrettner, MD

March/April 2018—A focus on multidisciplinary care.

The Benefits of Collaborative Care

Paul G. Matthew, MD, DNBPAS, FAAN, FAHS

March/April 2018— The National Academy of Medicine defines team-based care as any provision of health care by 2 or more medical professionals, who work collaboratively across settings, to a…


March/April 2018—Lawful Physician-Hastened Death, Hearing Loss and Cognitive Impairment, Extended-Release Amantadine, Fibromyalgia Biomarkers, Phase 3 Trial of Rimegepant for Migraine, A Blood Test for Concussion, and more.


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About Practical Neurology

Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.