Epilepsy & Seizures

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Food and Drug Administration Grants Breakthrough Therapy Designation for ZX008 for Treatment of Dravet Syndrome

Tuesday, February 06, 2018—Low-dose fenfluramine (ZX008, Zogenix) is classified as an orphan drug for the treatment of two rare forms of epilepsy: Dravet syndrome and Lennox-Gastaut syndrome. Positive r…

FDA Filing for Cannabidiol, Data on Diet and Exercise and Brain Aging and Memory, Boston Scientific Indication for DBS

January 2018—FDA Accepts NDA Filing of First Cannabis Plant-Derived Medicine On December 28, 2017, GW Pharmaceuticals announced that the US Food and Drug Administration (FDA) had accept…

Anti-Leucine–Rich Glioma-Inactivated 1 Antibody Encephalitis

Michelle L. Dougherty, MD

January 2018— Leucine-rich glioma-inactivated 1 (LGI1) antibody encephalitis is a recently described syndrome primarily characterized by seizures and cognitive decline. LGI1 antibody en…

ECTRIMS Data Signal Renewed Emphasis on Multiple Sclerosis Disease Progression, Disability

November/December 2017—Data presented at the Seventh Joint European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) -- Americas Committee for Treatment and Research in Multipl…

Forward Thinking: Advances in Neurology

November/December 2017—A review of notable neurological developments in 2017 and a preview of the year ahead.

Oral Vimpat Approved for Use in Pediatric Patients with Partial-Onset Seizures

Tuesday, November 07, 2017—The FDA approved a label extension for Vimpat (lacosamide, UCB) CV as an oral option for the treatment of partial-onset seizures (POS) in pediatric patients four years an…

In-Focus: Charting a New Course to Seizure Freedom

October 2017— VIDEO NEWS Managing Epilepsy in Pregnancy and Postpartum “What’s important now is that we think about how we’re going to mana

Advanced Epilepsy Care: Identifying Candidates for Surgical Interventions

Barbara C. Jobst, MD

October 2017—A growing platform of surgical interventions may increase awareness, referrals, and utilization of advanced treatment.


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.