Epilepsy & Seizures

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Clobazam Oral Film Approved For Treatment of Lennox-Gastaut Syndrome

Monday, November 05, 2018—The Food and Drug Administration (FDA) has approved an oral film clobazam (Sympazan; Aquestive Therapeutics, Warren, NJ) for the adjunctive treatment of seizures in patients, …

Epidiolex for Dravet Syndrome and Lennox Gastaut Syndrome Available for Prescription

Thursday, November 01, 2018—Pharmaceutical grade cannabidiol (CBD) (Epidiolex; Greenwich Biosciences, Carlsbad, CA), approved by the FDA for treatment of patients age 2 and up with Lennox-Gastaut Syndrom…

Disease-Modifying Treatment for Dravet Syndrome on the Horizon

Friday, October 05, 2018—A potentially disease-modifying therapy for Dravet syndrome (DS) being developed by Stoke Therapeutics (Bedford, MA) uses targeted augmentation of nuclear gene output (TANGO) …

Perampanel Now Approved by FDA for Patients With Epilepsy as Young as 4 Years

Monday, October 01, 2018—The Food and Drug Administration (FDA) has approved perampanel (Fycompa; Eisai, Woodcliff Lake, NJ) for use in children age 4 to 12 years. Before this decision, perampanel was…

Cannibidiol Rescheduling Clears Way for Distribution of FDA-Approved Cannabis-Derived Treatment for Dravet and Lennox-Gastaut Syndromes

Friday, September 28, 2018—The FDA-approved formulation of cannabidiol (CBD)(Epidiolex; GW Pharma, Carlsbad, CA) has been rescheduled by the Drug Enforcement Agency (DEA), clearing the way for marketing…

Patients With Epilepsy and Obstructive Sleep Apnea Have More Frequent Seizures

Tuesday, September 25, 2018—A pilot study of 49 adult patients with refractory focal, generalized, or unclassified epilepsy syndromes enrolled prospectively found those with probable obstructive sleep ap…

New Drug Application Filed for Diazepam Nasal Spray—an Investigational Treatment for Acute Repetitive Seizures

Tuesday, September 25, 2018—A new drug application has been filed with the Food and Drug Administration (FDA) for diazepam nasal spray (Valtoco; Neurelis, San Diego, CA), which is being investigated as a…

Presence of Nighttime Seizures May Increase Risk of Death in Patients With Epilepsy

Monday, September 24, 2018—Researchers have found that having nighttime seizures, especially generalized seizures at night, increases the risk of sudden unexpected death in epilepsy (SUDEP).(Neurology:S…


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