Epilepsy & Seizures

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Study Confirms Benefits of Laser Interstitial Thermal Therapy

Wednesday, November 14, 2018—A prospective, multi-center clinical study of 42 patients with brain lesions that recurred after stereotactic radiosurgery (SRS) for metastatic brain tumors showed p…

Clobazam Oral Film Approved For Treatment of Lennox-Gastaut Syndrome

Monday, November 05, 2018—The Food and Drug Administration (FDA) has approved an oral film clobazam (Sympazan; Aquestive Therapeutics, Warren, NJ) for the adjunctive treatment of seizures in patients, …

Epidiolex for Dravet Syndrome and Lennox Gastaut Syndrome Available for Prescription

Thursday, November 01, 2018—Pharmaceutical grade cannabidiol (CBD) (Epidiolex; Greenwich Biosciences, Carlsbad, CA), approved by the FDA for treatment of patients age 2 and up with Lennox-Gastaut Syndrom…

Disease-Modifying Treatment for Dravet Syndrome on the Horizon

Friday, October 05, 2018—A potentially disease-modifying therapy for Dravet syndrome (DS) being developed by Stoke Therapeutics (Bedford, MA) uses targeted augmentation of nuclear gene output (TANGO) …

Perampanel Now Approved by FDA for Patients With Epilepsy as Young as 4 Years

Monday, October 01, 2018—The Food and Drug Administration (FDA) has approved perampanel (Fycompa; Eisai, Woodcliff Lake, NJ) for use in children age 4 to 12 years. Before this decision, perampanel was…

Cannibidiol Rescheduling Clears Way for Distribution of FDA-Approved Cannabis-Derived Treatment for Dravet and Lennox-Gastaut Syndromes

Friday, September 28, 2018—The FDA-approved formulation of cannabidiol (CBD)(Epidiolex; GW Pharma, Carlsbad, CA) has been rescheduled by the Drug Enforcement Agency (DEA), clearing the way for marketing…

More and More Treatments: Are We There Yet?

Maromi Nei, MD

October 2018—New treatments—from cannabinoids to deep brain stimulation—may help meet the needs of still too many patients with uncontrolled seizures.

Hometown Highlights: Introducing Hometown Highlights

Stephen M. Gollomp, MD

October 2018—In this new column, we feature content from presenters at the 2018-2019 Philadelphia Neurological Society meetings.


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Launched in 2002, Practical Neurology is a publication uniquely dedicated to presenting current approaches to patient management, synthesis of emerging research and data, and analysis of industry news with a goal to facilitate practical application and improved clinical practice for all neurologists. Our straightforward articles give neurologists tools they can immediately put into practice.